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A “big break” is an expression that means, a significant opportunity or stroke of luck that advances a person’s career, fortunes, or prospects. It can be used in various contexts, such as in the entertainment industry, sports, business, or any other field where individuals are striving for success.
Botero’s big break came when the Museum of Modern Art bought one of his paintings. That signaled to the art world that he was to be taken seriously. It raised his profile and brought him new recognition and opportunity.
Other examples: The company’s big break came when Amazon featured its products on the home page. The actor’s big break came when he was cast in the starring role of a big-budget film.